Pomalidomide (cc-4047)

Pomalidomide (originally CC-4047), is a tumor necrosis factor-α inhibitor and a new immunomodulator with and IC50 of 1 μM. It i...

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YM 155

YM 155 is the first-in-class surviving inhibitor with an IC50 0.54 nM, selectively inhibits survivin expression and induces apoptosis in tumor cells. ...

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VX-765

VX-765 is a novel Caspase-1 inhibitor with an IC 50 of 0.8nM being investigated for the treatment of epilepsy, currently being developed ...

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