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BML-275
Chemical Information
M.Wt
472.41
Storage
Please store the product under ...
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MK 8033
MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet in...
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GDC 0349
GDC-0349 is a potent mTOR inhibitor. GDC0349 has entered in a phase I clinical trials in the treatment of Solid Tumors or Non Hodgkin's Lymphoma. [1]
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INK 128 (MLN 0218)
INK-128 (MLN-0218) is a potent and selective mTOR inhibitor with IC50 of 1 nM. TORC1/2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 com...
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PIK 75
PIK-75 blocks production of PIP2 and/or PIP3, phosphorylation of Akt, and activation of mTORC1 in adipocytes and myotubes. PI 3-kinase (PI3K) catalyze...
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Akt Inhibitor IV
Akt Inhibitor IV Inhibits Akt protein kinase. Reports indicate that Akt inhibitor IV targets the ATP-binding site of a kinase upstream of AKT and down...
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IPI 145 (INK 1197)
IPI-145 (INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM. IPI 145 is an orally bioava...
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VE 821
VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively. Inhibition of the key DNA damage ...
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Zotarolimus (ABT 578, A 179578)
Zotarolimus (ABT-578, A-179578) is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of reste...
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BYL 719
BYL-719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifi...
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BI-D1870
BI-D1870 is an ATP-competitive inhibitor of ribosomal S6 for RSK1, RSK2, RSK3 and RSK4 with IC50 of 31 nM, 24 nM, 18 nM and 15 nM, respectively. BI-D1...
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Tideglusib (NP 031112, NP12)
Tideglusib (NP031112, NP-12) is a potent non ATP-competitive inhibitor of GSK3 with IC50 of 60 nM. Glycogen synthase kinase 3 (GSK-3), a proline/serin...
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NU 7026
NU7026 is a DNA-PK inhibitor with IC50 of 0.23 μM. DNA-dependent protein kinase (DNA-PK) binds to strand breaks produced during normal cellular pro...
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TG 100713
TG100713 is a PI3K inhibitor for PI3Kg, PI3Kd, PI3Ka and PI3Kb with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively. TG-100713 inhibits endothel...
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TDZD 8
TDZD-8 is a noncompetitive GSK-3β inhibitor. GSK-3β is abundant in the central nervous system, particularly in the hippocampus, and plays a ...
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AZD 5363
AZD 5363 is a novel pyrrolopyrimidine derivative, and an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with...
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Apoptosis
Telomerase
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