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Products > Immunology/Inflammation > Toll-like Receptor (TLR) > TLR2-IN-C29
Product name : TLR2-IN-C29
Item : c2424
Price : 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
contact : Send inquiry to: info@acesobio.com
CAS : 363600-92-4
Molecular Weight : 285.29
Formula : C16H15NO4
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order.
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Details:
Description of:TLR2-IN-C29(cas:363600-92-4)
TLR2-IN-C29 is a potential TLR2 inhibitor.It is induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.

Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data. 

REFERENCES


1: Mistry P, Laird MH, Schwarz RS, Greene S, Dyson T, Snyder GA, Xiao TS, Chauhan J, Fletcher S, Toshchakov VY, MacKerell AD Jr, Vogel SN. Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5455-60. doi: 10.1073/pnas.1422576112. Epub 2015 Apr 13. PubMed PMID: 25870276; PubMed Central PMCID: PMC4418912.

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