Apoptosis
Telomerase
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Product name : GNE-477
Item : c2342
Price : 200mg, $1250;500mg, $2090; 1g, $2995;
contact : Send inquiry to: info@acesobio.com
CAS : 1032754-81-6
Molecular Weight : 504.63
Formula : C₂₁H₂₈N₈O₃S₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order.
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| Details: |
Description of:GNE-477
GNE-477(1032754-81-6)is a potent and efficacious dual PI3K (IC50=4 nM)/mTOR(Ki=21 nM) inhibitor.GNE-477 (Compound 8) has improved potency in the MCF7.1 cell proliferation assay with an EC50 of 143 nM. Quality control data: Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS. Product will be shipped with supporting analytical data. REFERENCES[1]. Heffron TP, et al. Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2408-11. |
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