Droxinostat/NS41080/NS-41080/NS 41080/99873-43-5/acesobio supply

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Product name : Droxinostat (NS 41080)

Item : cc490

Price : 200mg, $450;500mg, $850; 1g $1250; 2g, $1850

contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.

CAS : 99873-43-5

Molecular Weight : 243.69

Formula : C₁₁H₁₄ClNO₃

Storage : at -20°C

Additional information : We offer significant discount for larger quantity order

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Details:

Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8. Droxinostat shows comparable inhibition of HDAC6 and HDAC8 (IC50 = 2.47 and 1.46 μmol/L, respectively). Evasion of death receptor ligand-induced apoptosis represents an important contributor to cancer development and progression. This agent could sensitize malignant cells to death receptor ligands (FAS and TRAIL). ^[1]

Reference:

[1] Mol. Cancer Ther. 2010, 9, 246-256.

Chemical Information

Molecular Weight (WM):	243.69
Formula:	C₁₁H₁₄ClNO₃
CAS No:	99873-43-5
Purity:	≥ 98%
Synonyms:	NS41080, NS-41080
	DMSO ≥ 49 mg/mL
Solubility: (R.T.: 25℃):	Water < 1 mg/mL
	Ethanol ≥ 49 mg/mL
	2 years -20℃ Powder
Stability:	2 weeks -4℃ in DMSO
	2 months -80℃ in DMSO