Apoptosis
Telomerase
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Product name : AS 605240
Item : cc118
Price : 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 648450-29-7
Molecular Weight : 257.27
Formula : C₁₂H₇N₃O₂S
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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AS 605204 is a potent and selective inhibitor of PI 3-kinase γ (PI 3-Kγ) (IC50 = 8 nM). It displays 30-fold selectivity over PI 3-Kδ and PI 3-Kβ and 7.5-fold selectivity over PI 3-Kα. AS-605204 suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. It is orally active and ATP-competitive. [1][2]
Reference:
[1] J Neuroimmunol. 2010, 222, 90-94.
[2] Curr. Med. Chem. 2009, 16, 2839-2854.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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