Apoptosis
Telomerase
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Product name : TGX 221
Item : cc494
Price : 200mg, $750;500mg, $1250; 1g $1950; 2g, $3050
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 663619-89-4
Molecular Weight : 364.44
Formula : C₂₁H₂₄N₄O₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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TGX 221 is a cell-permeable morpholino-pyrimidinone compound that acts as a reversible, ATP-competitive, selective, and highly potent inhibitor of PI 3-Kb (p110b IC50 = 0.005 µM, p110d IC50 = 0.1 µM, p110a IC50 = 5 µM, and p110b IC50 ≥3.5 µM) with little activity against a panel of 15 commonly studied protein kinases even at concentrations as high as 10.0 µM. It is an excellent tool for studying p110b-dependent responses both in cells in vitro and in animals in vivo. [1][2]
Reference:
[1] Blood 2005, 106, 1432-1440.
[2] Blood 2006, 108, 3045-3952.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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