Apoptosis
Telomerase
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Product name : PI 103
Item : cc5
Price : 200mg, $650;500mg, $1050; 1g $1650; 2g, $2450
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 371935-74-9
Molecular Weight : 348.36
Formula : C₁₉H₁₆N₄O₃
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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PI 103 is an inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). It inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells. [1][2]
Reference:
[1] Leukemia 2008, 22, 1698-1706.
[2] Cell 2006, 19, 733-747.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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