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Products > PI3K/Akt/mTOR > ATM > KU 55933
Product name : KU 55933
Item : cc73
Price : 200mg, $650;500mg, $1050; 1g $1650; 2g, $2450
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 587871-26-9
Molecular Weight : 395.49
Formula : C₂₁H₁₇NO₃S₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
KU 55933 is a potent, selective and competitive ATM kinase inhibitor (Ki = 2.2 nM, IC50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Ku-55933 decreases viability of MCF-7, A549 and HCT116 cells and decreases p21CIP1 levels in vitro. It acts as a radio- and chemosensitizer for the treatment of cancer. [1][2]
 
Reference:
[1] Clin. Cancer Res. 2008, 15, 188-1887.
[2] Cancer Res. 2004, 64, 9152-9159.
 
 
Chemical Information
Molecular Weight (WM):
395.49
Formula:
C21H17NO3S2
CAS No:
587871-26-9
Purity:
≥ 98%
Synonyms:
KU60019, KU-60019
 
DMSO ≥ 50 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 13 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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