Apoptosis
Isocitrate dehydrogenase
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Product name : URB 597 (KDS-4103)
Item : cc135
Price : 200mg, $459;500mg, $750; 1g $1095; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 546141-08-6
Molecular Weight : 338.4
Formula : C₂₀H₂₂N₂O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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URB597 is a relatively selective fatty acid amide hydrolase (FAAH) inhibitor with IC50 of 4.6 and 0.5 nM in brain membranes and intact neurons, respectively. FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery where it activates cannabinoid receptors. In pre-clinical laboratory tests researchers found URB-597 increased the production of endocannabinoids resulting in measurable antidepressat and analgesic effects. [1][2]
Reference:
[1] J Med. Chem. 2004, 47, 4998-5008.
[2] Chem. Biol. 2005, 12, 1179-1187.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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