Apoptosis
CCR5
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Product name : Dolutegravir (S/SGSK1349572)
Item : cc13
Price : 1g, $650;2g, $950; 5g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1051375-16-6
Molecular Weight : 419.38
Formula : C₂₀H₁₉F₂N₃O₅
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Dolutegravir (GSK-1349572) is a novel potent integrase inhibitor with an IC50 of 2.7 nM in vitro. S/GSK-1349572 (GSK1349572) is a compound for the treatment of HIV infection. S/GSK 1349572 (GSK 1349572) exhibited in vitro activity against most clinical isolates obtained from patients failing RAL-based therapy. In PBMC cell assay, S/GSK1349572 inhibited HIV integrase with the antiviral IC50=0.51 and IC90=2.0 nM. [1][2]
Reference:
[1] Antimicrob. Agents Chemother. 2010, 54, 254-258.
[2] J Clin. Pharmacol. 2011, 51, 237-242.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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