Product name : Sunitinib malate (Sutent)
Item : cc354
Price : 5g, $650;10g, $1050; 20g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 341031-54-7
Molecular Weight : 532.56
Formula : C₂₆H₃₃FN₄O₇
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Sunitinib malate (Sutent) is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively). Sunitinib also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Sunitinib exhibits antiangiogenic and antitumor activity in multiple xenograft models. [1][2]
Reference:
[1] Nat. Rev. Drug Discov. 2007, 6, 734.
[2] Biochem. Biophys. Res. Commun. 2007, 356, 323-328.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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