Apoptosis
Sigma Receptor
|
Product name : VU 0357121
Item : cc377
Price : 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 433967-28-3
Molecular Weight : 305.32
Formula : C₁₇H₁₇F₂NO₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 |
| Details: | |||||||||||||||||||||||||
VU-0357121 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5) with EC50 = 33 nM, 92% Glumax. Its site of action is distinct from the classical mGlu5 negative allosteric modulator (NAM) MPEP allosteric site or the site of a recetly discovered PAM, CPPHA. However, VU 0357121 shares a functional interaction with the MPEP site. VU0357121 is highly selective for activation of mGlu5 and is inactive or very weakly antagonizing at other mGlu receptor subtypes. [1]
Reference:
[1] ACS Chem. Neruosci. 2010, 1, 702-716.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
| Related Products : |
|
|
|
|
Chinese
Deutsch
Espanol
Francais
Italiano
Portugues
Japanese
Korean
Arabic
Russian