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Product name : Obatoclax (GX15-070)
Item : cc-454
Price : 10mg, $295; 25mg, $495; 50mg, $795; 100mg, $1195
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
Obatoclax is an inhibitor of the Bcl-2 family of proteins with Ki of 0.22 μM. This inhibition induces apoptosis in cancer cells, preventing tumor growth. Obatoclax is an experimental drug candidate for the treatment of various types of cancer. It was discovered by Gemin X, which was acquired by Cephalon. It is in Phase II clinical trials for the treatment of leukemia, lymphoma, myelofibrosis, and mastocytosis.[1]
 
Reference:
[1] Cancer Res. 2008, 9, 3413-3420.
 
                                           
Chemical Information
Molecular Weight (WM):
413.49
Formula:
C20H19N3O·CH4O3S
CAS No:
803712-79-0
Purity:
≥ 98%
Synonyms:
GX15-070
 
DMSO ≥ 83 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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