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Products > Neuro Signaling > P2 Receptor > GW 791343
Product name : GW 791343
Item : cc223
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1019779-04-4
Molecular Weight : 447.35
Formula : C₂₀H₂₆Cl₂F₂N₄O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
GW-791343 hydrochloride is a non-competitive P2X7 allosteric modulator. GW791343 exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7.    [1][2]
 
Reference:
[1] Br. J Pharmacol. 2008, 153, 737-750.
[2] J Lipid Res. 2008, 155, 738-751.
 
 
Chemical Information
Molecular Weight (WM):
483.81
Formula:
C20H24F2N4O.3HCl
CAS No:
309712-55-8, 309712-73-0 (free base), 1019779-04-4
Purity:
≥ 98%
Synonyms:
GW 791343
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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