Product name : AZD 8330
Item : cc-458
Price : 200mg, $750;500mg, $1250; 1g $1850; 2g, $3050
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 869357-68-6
Molecular Weight : 461.23
Formula : C₁₆H₁₇FIN₃O₄
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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AZD 8330 is an orally active, selective MEK inhibitor with IC50 of 7 nM. MEK inhibitor AZD8330 specifically inhibits mitogen-activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers. [1]
Reference:
[1] Journal of Hematology & Oncology, 2010, 3,8
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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