Apoptosis
MAO
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Product name : Plerixafor (DB 06809, Mozobil, AMD 3100)
Item : cc304
Price : 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 110078-46-1
Molecular Weight : 502.78
Formula : C₂₈H₅₄N₈
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Plerixafor (DB06809, Mozobil, AMD3100) is a CXCR4 chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. Plerixafor blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. [1][2]
Reference:
[1] J Immunol. 2009, 183, 3204-3211.
[2] Biochem. Pharmacol. 2006, 72, 588-596.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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