Apoptosis
Aurora Kinase
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Product name : Kenpaullone
Item : cc567
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 142273-20-9
Molecular Weight : 327.18
Formula : C₁₆H₁₁BrN₂O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Kenpaullone is an ATP-competitive inhibitor of several CDKs (cyclin-dependent kinases) as well as GSK-3 (glycogen synthase kinase 3). It has been shown to inhibit GSK-3 with an IC50 value of 0.023 µM3 (0.23 µM) and CDK1/cyclin B, CDK2/cyclin A, CDK5/p25, and lymphocyte kinase with IC50 values of 0.4, 0.68, 0.85, and 0.47 µM, respectively. Due to the compound’s activity Kenpaullone is useful in the study of cell cycle regulators. [1][2]
Reference:
[1] Cancer Res. 1999, 59, 2566-2569.
[2] J Biol. Chem. 2001, 276, 251-260.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
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