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Product name : LY 315920 (Varespladib)
Item : cc80
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 172732-68-2
Molecular Weight : 380.39
Formula : C₂₁H₂₀N₂O₅
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
LY315920 (Varespladib) is a potent and selective secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM. LY-315920 acts as an anti-inflammatory agent by disrupting the first step of the arachidonic acid pathway of inflammation. LY 315920 has been under active investigation as a potential therapy for several inflammatory diseases, including acute coronary syndrome and acute chest syndrome. [1][2]
 
Reference:
[1] J Med. Chem. 1996, 39, 5159-5175.
[2] J Pharmacol. Exp. Ther. 1999, 288, 1117-1124.
 
 
Chemical Information
Molecular Weight (WM):
380.39
Formula:
C21H20N2O5
CAS No:
172732-68-2, 172733-42-5 (sodium salt)
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 76 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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