Product name : SB 590885
Item : cc-3
Price : 200mg, $1350;500mg, $1950; 1g $2650; 2g, $3750
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 405554-55-4
Molecular Weight : 453.54
Formula : C₂₇H₂₇N₅O₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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SB 590885 is an orally bioavailable inhibitor of B-raf (BRAF) protein with a Ki app of 0.16 ± 0.03 nM. Dabrafenib selectively binds to and inhibits the activity of B-raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B-raf belongs to the the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which may be constitutively activated due to BRAF gene mutations. [1]
Reference:
[1] Cancer Res. 2006, 66, 11100-11105.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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