Apoptosis
Btk
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Product name : AZD 8931 (Momelotinib)
Item : cc427
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 848942-61-0
Molecular Weight : 473.93
Formula : C₂₃H₂₅ClFN₅O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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| Details: | |||||||||||||||||||||||||
AZD8931 (Momelotinib) is a reversible, ATP competitive inhibitor of EGFR, erbB2 and erbB3 with IC50 of 4 nM, 3 nM and 4 nM, respectively. AZD-8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization. [1]
Reference:
[1] Clin. Cancer Res. 2010, 16, 1159-1169.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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