Apoptosis
Isocitrate dehydrogenase
|
Product name : Abiraterone (CB 7598)
Item : cc239
Price : 10mg, $225; 50mg, $695; 100mg, $1195; 200mg, $1895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : We offer significant discount for bulky quantity order
Molecular Weight :
Formula :
Storage :
Additional information :
 |
| Details: | |||||||||||||||||||||||||
Abiraterone (CB-7598) is a potent CYP17 inhibitor with IC50 of 2 nM. Abiraterone (CB7598) inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. [1][2]
Reference:
[1] J Clin. Oncol. 2008, 26, 4563-4571.
[2] J Med. Chem. 2010, 53, 5749-5758.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
| Related Products : |
|
|
|
|
Chinese
Deutsch
Espanol
Francais
Italiano
Portugues
Japanese
Korean
Arabic
Russian