Apoptosis
Btk
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Product name : AMG 458
Item : cc602
Price : 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 913376-83-7
Molecular Weight : 539.58
Formula : C30H29N5O5
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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| Details: | |||||||||||||||||||||||||
AMG458 is a Potent, Selective, and Orally Bioavailable c-Met Inhibitor with Ki=2.0, IC50(CT26)=120 nM significantly inhibited tumor growth in the NIH3T3/TPR-Met and U-87 MG xenograft models with no adverse effect on body weight. [1][2]
Reference:
[1] J Med. Chem. 2008, 51, 3688-3691.
[2] Chem. Res. Toxicol. 2008, 21, 2216-2222.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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