Product name : TAK 733
Item : cc621
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1035555-63-5
Molecular Weight : 504.23
Formula : C₁₇H₁₅F₂IN₄O₄
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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TAK-733 is a potent, selective, ATP-noncompetitive MEK allosteric site inhibitor with an IC50 of 3.2 nM. TAK733 selectively binds to and inhibits the activity of MEK1/2. TAK 733 prevents the activation of MEK1/2-dependent effector proteins and transcription factors, which mayresult in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation. [1][2]
Reference:
[1] Bioorg. Med. Chem. Lett. 2011, 21, 1315-1319.
[2] Mol. Cancer 2012, 11, 22.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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