CX 4945/silmitasertib/CX4945/CX-4945/1009820-21-6/1309357-15-0/acesobio supply

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Product name : CX 4945 (silmitasertib)

Item : cc639

Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590

contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.

CAS : 1009820-21-6

Molecular Weight : 349.77

Formula : C₁₉H₁₂ClN₃O₂

Storage : at -20°C

Additional information : We offer significant discount for bulky quantity order

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Details:

CX 4945 (Silmitasertib) is an orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. CX-4945 selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumor growth and survival. ^[1][2]

Reference:

[1] Cancer Res. 2010, 70, 10288-10298.

[2] Mol. Cell Biochem. 2011, 356, 37-43.

Chemical Information

Molecular Weight (WM):	349.77
Formula:	C₁₉H₁₂ClN₃O₂
CAS No:	1009820-21-6, 1309357-15-0 (sodium salt)
Purity:	≥ 98%
Synonyms:	CX4945
	DMSO ≥ 16 mg/mL
Solubility (25℃)	Water < 1 mg/mL
	Ethanol < 1 mg/mL
	2 years -20℃ Powder
Stability:	2 weeks -4℃ in DMSO
	2 months -80℃ in DMSO

Quality control data:

Quality control by ¹H-NMR, ¹³C-NMR, HPLC and LCMS.

Product will be shipped with supporting analytical data.

PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.

NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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