Apoptosis
MAO
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Product name : Pentostatin
Item : cc 681
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 53910-25-1
Molecular Weight : 268.27
Formula : C₁₁H₁₆N₄O₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Pentostatin is an extremely potent (Ki = 2.5 pM) irreversible inhibitor of adenosine deaminase. Pentostatin inhibition of ADA appears to result in elevated intracellular levels of dATP which may block DNA synthesis through the inhibition of ribonucleotide reductase. This agent may also inhibit RNA synthesis and may selectively deplete CD26+ lymphocytes. [1][2]
Reference:
[1] Cancer Res. 1981, 41, 4508-4511.
[2] Biochem. Pharmacol. 1982, 31, 3961-3971.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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