Product name : VE 821
Item : cc 726
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
CAS : 1232410-49-9
Molecular Weight : 368.41
Formula : C₁₈H₁₆N₄O₃S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively. Inhibition of the key DNA damage response kinase ATR has been suggested as an attractive approach for sensitization of tumor cells to DNA damaging agents. [1][2]
Reference:
[1] Nat. Chem. Biol. 2011, 7, 428-430.
[2] J Med. Chem. 2011, 54, 2320-2330.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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