Apoptosis
Serotonin Transporter
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Product name : LY 344864
Item : cc757
Price : 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com
CAS : 186544-26-3
Molecular Weight : 351.42
Formula : C₂₁H₂₂FN₃O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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LY-344864 is a potent, selective 5-HT1F receptor agonist (EC50 = 3 nM). LY344864 displays > 80-fold selectivity over other 5-HT receptors (Ki values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μM for 5-HT1F, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT2B, 5-HT2C, 5-HT2A and 5-HT7 receptors respectively). Furthermore LY 344864 hydrochloride has been shown to inhibit neurogenic dural inflammation in vivo. [1][2]
Reference:
[1] Neuroscience, 2003, 122, 491-498.
[2] Cephalagia, 2003, 23, 776-785.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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