Apoptosis
DHFR
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Product name : Ixabepilone (BMS -247550)
Item : cc806
Price : 200mg, $1750;500mg, $2890; 1g, $3950;
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
CAS : 219989-84-1
Molecular Weight : 506.7
Formula : C₂₇H₄₂N₂O₅S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Ixabepilone (BMS-247550) is an orally bioavailable semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. [1][2]
Reference:
[1] Clin. Cancer Res. 2001, 7, 1429-1437.
[2] Cancer Res. 2002, 62, 466-471.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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