Product name : NSC 42834
Item : CR1957
Price : 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
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CAS : 195371-52-9
Molecular Weight : 344.45
Formula : C₂₃H₂₄N₂O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Chemical Information
Biological Activity of NSC 42834
NSC 42834(JAK2 Inhibitor V, Z3), a novel specific inhibitor of Jak2, inhibits Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner but was not cytotoxic to cells at concentrations that inhibited kinase activity.
References on NSC 42834[1]. Jacqueline Sayyah, Andrew Magis, David A. Ostrov, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth . Mol Cancer Ther 2008;7(8):2308-18. |
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