Product name : CGP 57380
Item : CR1820
Price : 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com
CAS : 522629-08-9
Molecular Weight : 244.23
Formula : C₁₁H₉FN₆
Storage :
Additional information :
|
Details: | ||||||||||
Chemical Information
Biological Activity of CGP 57380
CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 (IC50 = 2.2 μM) with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases.
References on CGP 57380[1]. Worch J, et al. The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cells. Oncogene. 2004 Dec 9;23(57):9162-72. |
Related Products : |