Apoptosis
DHFR
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Product name : Exatecan
Item : cc173
Price : 500mg $6590; 1g, $9190
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 171335-80-1
Molecular Weight : 435.45
Formula : C₂₄H₂₂FN₃O₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. [1][2]
Reference:
[1] Clin. Cancer Res. 2002, 8, 2134-2141.
[2] Clin. Cancer Res. 2001, 7, 3056-3064.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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