Product name : Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin)
Item : cc808
Price : 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590
contact : Send inquiry to: info@acesobio.com
CAS : 57852-57-0
Molecular Weight : 533.95
Formula : C₂₆H₂₈ClNO₉
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds. [1][2]
Reference:
[1] J Chemother. 2005, 17, 663-667.
[2] Hematology. 2004, 9, 217-221.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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