Apoptosis
DPP4
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Product name : SNX 2112
Item : cc397
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 908112-43-6
Molecular Weight : 464.48
Formula : C₂₃H₂₇F₃N₄O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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SNX-2112 selectively binds to the ATP pocket of Hsp90 family members Hsp90α and Hsp90β with Ka of 30 nM and 30 nM, respectively. In all cell lines, SNX2112 led to degradation of MET, HER-2, EGFR, and AKT as well as abrogation of Ras/Raf/MEK/MAPK and PI3K/AKT signaling, followed by complete cell cycle arrest. [1][2]
Reference:
[1] Biosci. Biotechnol. Biochem. 2011, 75, 1540-1545.
[2] Biomed. Pharmacother. 2011, 65, 132-136.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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