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Products > GPCR > mGluR > ADX 47273
Product name : ADX 47273
Item : cc252
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 851881-60-2
Molecular Weight : 369.36
Formula : C₂₀H₁₇F₂N₃O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
ADX47273 is a potent and specific mGlu5 receptor antagonist with IC50 of 0.17μM. ADX-47273 has nootropic and antipsychotic effects in animal studies, and has been used as a lead compound to develop improved derivatives. [1][2]
 
Reference:
[1] J Med. Chem. 2006, 49, 3332-3344.
[2] J Pharmacol. Exp. Ther. 2008, 327, 827-839.
 
 
Chemical Information
Molecular Weight (WM):
369.36
Formula:
C20H17F2N3O2
CAS No:
851881-60-2
Purity:
≥ 98%
Synonyms:
ADX 47273
 
DMSO ≥ 74 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 27 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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