Product name : Pifithrin-α
Item : cc 688
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 63208-82-2
Molecular Weight : 367.3
Formula : C₁₆H₁₉BrN₂OS
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. It enhances cell survival after genotoxic stress such as UV irradiation and treatment with cytotoxic compounds including doxorubicin, etopoxide, paclitaxel, and cytosine-β-D-arabinofuranoside. Pifithrin-α protects against neuronal death in models of stroke and neurodegenerative disorders. [1][2]
Reference:
[1] Science 1999, 285, 1733-1737.
[2] Biochemistry 2000, 65, 41-48.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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