Apoptosis
Btk
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Product name : ZM323881 hydrochloride
Item : cc 699
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 193000-39-4
Molecular Weight : 411.86
Formula : C₂₂H₁₉ClFN₃O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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ZM-323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other receptor tyrosine kinases, including VEGF-R1 (IC(50) > 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro. [1][2]
Reference:
[1] J Recept. Signal Transduct. Res. 2003, 23, 239-254.
[2] J Clin. Endocrinol. Metab. 2006, 91, 4603-4611.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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