Apoptosis
MNK
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Product name : PLX 4720
Item : cc-4
Price : 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 918505-84-7
Molecular Weight : 413.83
Formula : C₁₇H₁₄ClF₂N₃O₃S
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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PLX 4720, developed by Plexxikon, Inc., is a 7-azaindole derivative that inhibits B-Raf (V600E) with an IC50 of 13 nM, defines a class of kinase inhibitor with marked selectivity in both biochemical and cellular assays. PlX 4720 preferentially inhibits the active B-Raf (V600E) kinase compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing the V600E allele. [1][2]
Reference:
[1] Nature, 2010, 464(7287), 427-430.
[2] Nature, 2010, 464(7287), 431-435.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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